GO@L GEnOmique @ Lille) is the genomics platform of the PLBS unit (UAR2014-US41). It provides a wide range of solutions and expertise in the field of high-throughput genomics. The technical approaches used are mainly based on high-throughput sequencing and DNA chips. The platform is the result of the merger of two specific and long-established entities, TAG (Transcriptomic and applied genomic) and GFS (Functional and structural genomics), and over the years has developed recognised expertise in microbiology and human genomics.

GO@L offers RNA quantification approaches (mRNA, small RNA, lncRNA, isoforms, single-cell, spatial) in a targeted manner or at the genome level for differential expression analyses, approaches for the identification and quantification of DNA anomalies (target-Seq, WES, WGS), approaches for DNA-DNA and DNA-RNA interactions and for the regulation of gene expression (ChIP-Seq, RIP-Seq, DNAse-Seq, methylation) GO@L has also developed a specialisation in microbial genomics with whole genome sequencing applications for bacteria and viruses, classical and dedicated RNA-seq applications such as differential RNA-seq and 5’RACE-NGS and a complete pipeline of targeted metagenomic studies.

The GO@L team is composed of half molecular biologists specialised in high throughput and half bioanalysts and bioinformaticians who are experts in the analysis of the data generated and the development of dedicated solutions.